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Wuhan Wang Lianshang Biotechnology Co., Ltd.

Orlistat, Orlipastat, 96829-58-2 manufacturer / supplier in China, offering Orlistat CAS: 96829-58-2 for Weight Loss Powder Orlipastat Body Glittering, 99% Manufacturer Supply High Quality Industrial Salt/Sodium Chloride, 99% Thymosin Beta-4 CAS No. 77591-33-4 Tb 500 Peptide for Muscle Growth and so on.

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Supplier Homepage Product pharmaceutical intermediate Orlistat CAS: 96829-58-2 for Weight Loss Powder Orlipastat Body Glittering

Orlistat CAS: 96829-58-2 for Weight Loss Powder Orlipastat Body Glittering

FOB Price: US $300 / kg
Min. Order: 100 gram
Min. Order FOB Price
100 gram US $300/ kg
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Production Capacity: 250kg /Month
Transport Package: 25kg/ Drum
Payment Terms: L/C, T/T, Western Union, Money Gram

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Basic Info
  • Model NO.: 96829-58-2
  • CAS: 96829-58-2
  • Molecular Weight: 495.7348
  • Efficacy: Weight Loss & Slimming
  • Synonyms: Orlipastat
  • Specification: Medical grade
  • HS Code: 7845495
  • Product Name: Orlistat
  • Molecular Formula: C29h53no5
  • Purity: 99%
  • Appearance: White Powder
  • Trademark: Newwork union
  • Origin: China
Product Description
Orlistat CAS:96829-58-2 for Weight Loss Powder Orlipastat Body Glittering 


 

Product Name
Orlistat
Synonyms(S)-2-FORMYLAMINO-4-METHYL-PENTANOIC ACID (S)-1-[[(2S,3S)-3-HEXYL-4-OXO-2-OXETANYL]METHYL]-DODECYL ESTER; RO-18-0647; (-)-TETRAHYDROLIPSTATIN; N-FORMYL-L-LEUCINE (1S)-1-[[(2S,3S)-3-HEXYL-4-OXO-2-OXETANYL]METHYL]DODECYL ESTER; ; (-)-Tetrahydrolipstatin(EquivalentToOrlistat); Orlipastat; (1S)-1-{[(2R,3S)-3-hexyl-4-oxooxetan-2-yl]methyl}dodecyl N-formyl-D-leucinate; [(1S)-1-[[(2S)-3-hexyl-4-oxo-oxetan-2-yl]methyl]dodecyl] (2S)-2-formamido-4-methyl-pentanoate
Molecular FormulaC29H53NO5
Molecular Weight495.7348
InChIInChI=1/C29H53NO5/c1-5-7-9-11-12-13-14-15-16-18-24(34-29(33)26(30-22-31)20-23(3)4)21-27-25(28(32)35-27)19-17-10-8-6-2/h22-27H,5-21H2,1-4H3,(H,30,31)/t24-,25?,26-,27-/m0/s1
CAS Registry Number96829-58-2
Molecular Structure 
Density0.976g/cm3
Boiling point615.9°C at 760 mmHg
Refractive index1.469
Flash point326.3°C
Vapour Pressure4.23E-15mmHg at 25°C
Assay99%
AppearanceWhite or white powder
 


Orlistat (also known as tetrahydrolipstatin) is a drug designed to treat obesity. It is marketed as a prescription drug under the trade name by Roche in most countries, and is sold over-the-counter as by GlaxoSmithKline in the United Kingdom and the United States.Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.
 
Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini.However, due to its relative simplicity and stability, orlistat was chosen over lipstatin for development as an anti-obesity drug.
 
The effectiveness of orlistat in promoting weight loss is definite, though modest. Pooled data from clinical trials suggest that people given orlistat in addition to lifestyle modifications, such as diet and exercise, lose about 2-3 kilograms (4.4-6.6 lb) more than those not taking the drug over the course of a year.Orlistat also modestly reduces blood pressure, and appears to prevent the onset of type 2 diabetes, whether due to weight loss itself or to other effects; in a large randomized controlled trial, orlistat was found to reduce the incidence of diabetes by nearly 40% in obese people.
 
Orlistat is notorious for its gastrointestinal side effects (sometimes referred to as treatment effects), which can include steatorrhea (oily, loose stools). These decrease with time, however, and are the most frequently reported adverse effects of the drug.In the United States and the European Union, orlistat is available for sale without a prescription. Over-the-counter approval was controversial in the United States, with consumer advocacy group Public Citizen repeatedly opposing it on safety and efficacy grounds.Generic formulations of orlistat are available in some countries. In Australia it is listed as an S3 medication, which means it's available over the counter in pharmacies.
 
At times, such as in spring 2012, orlistat has come into short supply, with consequent price increases because of nonavailability of one of the drug's components.
 
 
Medical uses
 
Orlistat is used for the treatment of obesity. The amount of weight loss achieved with orlistat varies. In one-year clinical trials, between 35.5% and 54.8% of subjects achieved a 5% or greater decrease in body mass, although not all of this mass was necessarily fat. Between 16.4% and 24.8% achieved at least a 10% decrease in body fat.After orlistat was stopped, a significant number of subjects regained weight-up to 35% of the weight they had lost.
 
The incidence of type 2 diabetes in an obese population over four years is decreased with orlistat (6.2%) compared to placebo (9.0%).Long-term use of orlistat also leads to a modest reduction in blood pressure (mean reductions of 2.5 and 1.9 mmHg in systolic and diastolic blood pressure respectively).
 
Tag:Fat Loss Powders;Orlistat;Orlipastat;Weight Loss Steroids
 


 

ITEMS

SPECIFICATIONS

RESULTS

DESCRIPTION

White or off-white 
crystalline powder

White crystalline 
powder

IDENTIFICATION

The retention time of the
major peak in the
 chromatogram of the Assay
preparation corresponds to 
that in the chromatogram of 
the standardpreparation, as 
obtained in the Assay. IR
 spectrum correspondends
to standard preparation.

Conforms

MELTING POINT 
(MELTING POINT APPARATUS)

42~45°C

42.5~44.0°C
 

SPECIFIC 
ROTATION(CHLOROFORM1.0%)

-32 °~-36°

-34.2°

WATER(K.Fisher)

≤0.5%

0.30%

RESIDUE ON IGNITION  

≤0.2%

0.08%

HEAVY METALS  

≤0.00001

Conforms

RESIDULE SOLVENT
(GAS CHROMATOGRAPHY)

 
Ethanol ≤0.5%  
N-heptane ≤0.5%

 
0.001%
0.11%
 

RELATED SUBSTANCE 

2.0%(The sum of the areas
 of all impurity peaks in the chromatogram obtained 
with test solution is not 
greater than the area of the
 principal peak in the
 chromatogram obtained
 with reference solution.)

1.70%
 

PURITY(DRY BASIS HPLC)

≥98.0%

98.30%

CONCLUSION

Enterprise Standard

Conforms 

 

 
 Packaging & Delivery:
 
We have professional team for package and shipment. Special way to ship 100 grams to 100kg powders at one time to your country. Fast and discreet shipment could be arranged for customs pass Guaranteed.
 

 Our advantages:
 
 Our company is a professional raw powder factory in China for over 10  years, all powders are factory directly supplying.
 Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France,  Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month.
 Professional team special for package and shipment and staring on tracking code 24hours for  customs pass guaranteed. 100% pass to UK, Norway, Poland, Spain, USA, Canada, Brazil;  98% pass to Germany, Russia, Australia, New Zealand.
 Most of powders are in stock, Chargeable samples are available, Could be shipped out within  24hours.
 High quality, good price, fast and safety delivery. Shipment by DHL, TNT, FEDEX, HKEMS,  UPS, etc. 


 

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