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Wuhan Wang Lianshang Biotechnology Co., Ltd.

Dxm Powder, Pharmaceutical Chemical, Pharmaceutical Intermediate manufacturer / supplier in China, offering Raw Pure Powder Dextromethorphan Hydrobromide Dxm for Sexy Figure, GMP Pharmaceutical Manufacturer Levetiracetam 102767-28-2, Chemical Cosmetics 501-30-4 China Kojic Acid for Skin Care and so on.

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Supplier Homepage Product pharmaceutical intermediate Raw Pure Powder Dextromethorphan Hydrobromide Dxm for Sexy Figure

Raw Pure Powder Dextromethorphan Hydrobromide Dxm for Sexy Figure

FOB Price: US $1 / g
Min. Order: 100 g
Min. Order FOB Price
100 g US $1/ g
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Port: Hong Kong, Hong Kong
Production Capacity: 1000kg
Payment Terms: T/T, Western Union, Money Gram

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Basic Info
  • Model NO.: 125-69-9
  • Customized: Non-Customized
  • Suitable for: Elderly, Adult
  • Purity: >99%
  • Delivery: EMS, DHL, TNT, FedEx, UPS
  • Trademark: Wang Lianshang
  • Specification: USP
  • HS Code: 3004201500
  • Powder: Yes
  • Certification: ISO 9001, USP, BP
  • State: Solid
  • Appearance: White Powder
  • Storage: Keep in Cool and Dry Place, Away From Light
  • Transport Package: Foil Bag or Drum
  • Origin: HK
Product Description

1.Basic Info.

Product Name:Dextromethorphan Hydrobromide
Alias :Dextromethorphan Hbr , Dextromethorphan Hydrobromicum , Dextromethorphan Hydrobromide , , Romilar
Dextromethorphan Hydrobromide
Alias:Romilar
CAS No.:125-69-9
EINECS No.:204-750-1
MF:C18H26BrNO
MW:352.31
Purity:98.0%
Appearance:White or kind of white crystalline powder, soluble in water.




2.Description:

Dextromethorphan (DXM or DM) is an antitussive (cough suppressant) drug. It is one of the active ingredients in many over-thecounter cold and cough medicines, including generic labels and store brands, Benylin DM, Mucinex DM, Robitussin, NyQuil, Dimetapp, Vicks, Coricidin, Delsym, TheraFlu, and others.

Dextromethorphan has also found other uses in medicine, ranging from pain relief to psychological applications. It is sold in syrup, tablet, spray, and lozenge forms. In its pure form, dextromethorphan occurs as a white powder.




3.Application:

DXM is also used recreationally.When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative hallucinogen.Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist.

The major metabolite of DXM, dextrorphan, also acts as an NMDA receptor antagonist.In high doses this produces effects similar to, yet distinct from, the dissociative states created by other dissociative anaesthetic such as and .As well, the metabolite 3-methoxymorphinan of dextrorphan (thus a second-level metabolite of DXM) produces local anesthetic effects in rats with potency above dextrorphan, but below that of DXM.




4.Use:

1. For dry cough, including upper respiratory tract infection (such as cold, pharyngitis, bronchitis, cough).

2. Research reagents, widely used in molecular biology, pharmacology research. This is the central antitussive, can inhibit the medulla cough centrum antitussive effect and produce. The antitussive effect is equal to or slightly. The general treatment dose not inhibit respiration, long-term use of no addiction and tolerance.




5.Medical use

Generic Dextromethorphan syrup.

The primary use of dextromethorphan is as a cough suppressant, for the temporary relief of cough caused by minor throat and bronchial irritation (such as commonly accompanies the flu and common cold), as well as those resulting from inhaled particle irritants.

A 2004 study showed that dextromethorphan was no more effective for children than a placebo.Studies conducted by the American Academy of Pediatrics show that dextromethorphan is not superior to a placebo in providing nocturnal symptom relief for children with cough and sleep difficulty due to upper respiratory infections.

A combination of dextromethorphan and quinidine, a CYP2D6 inhibitor, has been shown to alleviate symptoms of easy laughing and crying (pseudobulbar affect) in patients with amyotrophic lateral sclerosis and multiple sclerosis.Dextromethorphan is also being investigated as a possible treatment for neuropathic pain and pain associated with fibromyalgia.In 2010, the FDA approved the combination product dextromethorphan/quinidine (Nuedexta) for the treatment of pseudobulbar affect (PBA).

Dextromethorphan has been shown to be effective in treating opioid withdrawal. At doses of 2 mg/kg in rats all signs of opioid withdrawal were eliminated.




6.COA: 
 
TESTSPECIFICATIONTEST RESULT
ApperancePractically white crystal or
crystalline powder
White crystalline powder
IdentificationA. FT-IRThe sample spectrum correspond to
that of the reference standard
Conforms
B. UVNot more than 3.0% difference
of RS(on anhydrous basis)
1.4%
C. Bromide TestYellow white precipitate formedConforms
Specific rotation A1.8w/v in water:Not more than 1.0%
difference of RS
At 325nm and 25ºC(on anhydrous basis)
0.23%
Specific rotation B2.0%w/v in 0.1M HCL: +28ºCto +30ºC
at 589nm and 20ºC(on anhydrous basis)
+28.2ºC
Clarity of solution5.0%w/v in alcohol:Clear and colorlessConforms
PH5.2-6.5(1 in 100 water solution)6.1
Acidity or AlkalinityNot more than 0.4ml of
0.01M HCLconsumed
0.24ml
Water(by KF Titration)4.0%-5.5%5.0%
Relates substances
(by HPLC;ph;Eur)
a)For each of impurities A,B,C,D
not more than 0.5%
Impurities A,B,C,D;
Not detected.
 
b)Among impurities A,B,C,D not
more than one greater than 0.25%
0
C)For each of unspecified impurities,
not more than0.10%
<0.05%
d)Total impurities not more than 1.0%<0.05%
Residue on IgnitionNot more than 1.0%0.05%
N,N-DimethylanilineNot more than 0.001%Conforms
Phenolic compoundsNo blue-green color developsConforms
Assay A (by HPLC)98.0%~102.0%(on anhydrous basis)100.0%
Assay B(by titration)99.0%~101.0%(on anhydrous basis)100.4%
Residual solventsMethanol≤3000ppm

Toluene≤890ppm

Acetone≤5000ppm
52ppm

0.8ppm

2ppm
StoragePreserve in tight containers;
protected from light
Conforms
Compliance StatementUSP35/EP7




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Payment
T/T , Western Union, Money Gram, Bitcoins.


Our Advantages:
1.Rich experience.We are a professional trading company in China for many years,our products have exported to Germany,Spain,UK,USA,Australia,Middle East and so many other countries,and we have got very good feedback from our customers,we had Established many long friendly relations of cooperation.
2.Great quality,purity and competitive price.
3.Safe and fast delivery.
4.Good after-sales service.

Tracking number:
EMS:
EA276218706HK
EA276076852HK
EA272838620HK
DHL:
8124222794
1667845944
6338036386

Welcome to inquiry!



If you have any requirement, just be free to contact us.

Tina
 
 
 


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