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Wuhan Wang Lianshang Biotechnology Co., Ltd.

Raloxifene Hydrochloride, 82640-04-8, Raloxifene HCl manufacturer / supplier in China, offering 82640-04-8 Light Yellow Raloxifene HCl Powder Raloxifene Hydrochloride, Quality Guaranteed Raw Powder and Injectable 250mg/Ml Enanject 250 Testosterone Enanthate, 100% Purified Hot Sell Muscle Building Steroid Deca 200 Nandrolone Decanoate Steroid Hormone Powder and so on.

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Supplier Homepage Product pharmaceutical intermediate 82640-04-8 Light Yellow Raloxifene HCl Powder Raloxifene Hydrochloride

82640-04-8 Light Yellow Raloxifene HCl Powder Raloxifene Hydrochloride

FOB Price: US $30 / kg
Min. Order: 1 kg
Min. Order FOB Price
1 kg US $30/ kg
Get Latest Price
Production Capacity: 200kg /Month
Transport Package: 1kg/ Foil Bag
Payment Terms: L/C, T/T, Western Union, Money Gram
Basic Info
  • Model NO.: 82640-04-8
  • CAS: 82640-04-8
  • Molecular Weight: 475.5992
  • Storage: Shading, Confined Preservation
  • Synonyms: Raloxifene HCl
  • Specification: ISO9001
  • HS Code: 29095090
  • Product Name: Raloxifene Hydrochloride
  • Molecular Formula: C28h29no4s
  • Purity: 99%
  • Appearance: Light Yellow Powder
  • Trademark: Newwork union
  • Origin: China
Product Description
82640-04-8 Light Yellow Raloxifene HCl Powder Raloxifene Hydrochloride

Quick Detail:
Raloxifene hydrochloride
Alias: Raloxifene HCL;
CAS :82640-04-8
Purity: 99%
MF: C28H28ClNO4S
MW: 510.04
Appearance:light yellow powder
Usage :It is used in the prevention of osteoporosis in postmenopausal women.

Description:
EVISTA (raloxifene hydrochloride) is an estrogen agonist/antagonist, commonly referred to as a selective estrogen receptor modulator (SERM) that belongs to the benzothiophene class of compounds. 
Raloxifene hydrochloride (HCl) has the empirical formula C28H27NO4SHCl, which corresponds to a molecular weight of 510.05. Raloxifene HCl is an off-white to pale-yellow solid that is very slightly soluble in water.
EVISTA (raloxifene) is supplied in a tablet dosage form for oral administration. Each EVISTA tablet contains 60 mg of raloxifene HCl, which is the molar equivalent of 55.71 mg of free base. Inactive ingredients include anhydrous lactose, carnauba wax, crospovidone, FD&C Blue No. 2 aluminum lake, hypromellose, lactose monohydrate, magnesium stearate, modified pharmaceutical glaze, polyethylene glycol, polysorbate 80, povidone, propylene glycol, and titanium dioxide.

Applications:
Raloxifene is used to prevent and treat bone loss (osteoporosis) in women after menopause. Maintaining strong bones by slowing bone loss helps to reduce the risk of fractures.
Raloxifene may also lower the chance of getting a certain type of breast cancer (invasive) in women after menopause.
This drug is different from hormones (including estrogens and progestins). It works by acting like estrogen (as a selective estrogen receptor modulator or SERM) in some parts of the body. Raloxifene helps to preserve bone mass, but it does not affect the breast and uterus like estrogen or relieve symptoms of menopause such as hot flashes.
This medication is not recommended for use in women before menopause. It should not be used in children...
Side effect: Raloxifene may infrequently cause serious blood clots to form in the legs, lungs, oreyes. Other reactions experienced include leg swelling/pain, trouble breathing, chest pain, vision changes. Raloxifene is a teratogenic drug, i.e., can cause developmental abnormalities such as birth defects.


May prevent or treat corticosteroid-induced bone loss. American College of Rheumatology states that raloxifene can be offered to selected postmenopausal corticosteroid-treated women who refuse hormone replacement therapy or other antiresorptive agents (e. G., bisphosphonates, calcitonin) or in whom such therapies are contraindicated.

Reduction in the incidence of invasive breast cancer in postmenopausal women with osteoporosis.

Reduction in the incidence of invasive breast cancer inpostmenopausal women at high risk for developing the disease. Effect comparable to that of tamoxifen in reducing the risk of invasive breast cancer (STAR trial). No effect on the risk of lobular carcinoma in situ or ductal carcinoma in situ (STAR trial). Effect on breast cancer incidence in women with BRCA1 or BRCA2 genetic mutations not established.

Not indicated for the treatment of breast cancer or to reduce the risk of recurrence of breast cancer. 1 Not indicated for reduction in the risk of noninvasive breast cancer.

Side effect: Raloxifene may infrequently cause serious blood clots to form in the legs, lungs, or eyes. Other reactions experienced include leg swelling/pain, trouble breathing, chest pain, vision changes. Raloxifene is a teratogenic drug, i. e., can cause developmental abnormalities such as birth defects.

Specifications:


MS

SPECIFICATION

RESULT

Characters
  

Appearance

White &off-white powder

Conform

 
Solubility

Soluble in 10% sodium hydroxide solution. Slightly Soluble in methanol. Insoluble in water

 
Conform

Identifications

Infrared Absorption

Conform
 
Chloride

Conform

Tests

Loss on drying

≤0.5%

0.4%
 
Residue on ignition

≤0.1%

0.06%
 
Heavy metals

≤10ppm

Conform

 
RRelated substances

 

≤0.20 %

0.10%
 
Any unspecified individual impurity 2

≤0.10%

Max. 0.08%
 
Total impurities

≤0.50%

0.40%

Assay

Raloxifene HCl

≥98.0%

99.0%
 
 



 Packaging & Delivery:
 
We have professional team for package and shipment. Special way to ship 100 grams to 100kg powders at one time to your country. Fast and discreet shipment could be arranged for customs pass Guaranteed.
 

 Our advantages:
 
 Our company is a professional raw powder factory in China for over 10  years, all powders are factory directly supplying.
 Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France,  Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month.
 Professional team special for package and shipment and staring on tracking code 24hours for  customs pass guaranteed. 100% pass to UK, Norway, Poland, Spain, USA, Canada, Brazil;  98% pass to Germany, Russia, Australia, New Zealand.
 Most of powders are in stock, Chargeable samples are available, Could be shipped out within  24hours.
 High quality, good price, fast and safety delivery. Shipment by DHL, TNT, FEDEX, HKEMS,  UPS, etc. 


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