CAS 21462-39-5 Lincomycin Hydrochloride, Clindamycin Hydrochloride & Clindamycin Phosphate 24729-96-2
|FOB Price:||US $15 / kg|
|Min. Order:||1 kg|
|Min. Order||FOB Price|
|1 kg||US $15/ kg|
|Production Capacity:||250kg /Month|
|Transport Package:||25kg/ Drum|
|Payment Terms:||L/C, T/T, Western Union, Money Gram|
- Model NO.: 21462-39-5
- CAS: 21462-39-5
- Molecular Weight: 443.06
- Einecs: 244-398-6
- Synonyms: Lincomycin HCl, Lincomycin, Clindamycin HCl
- Specification: ISO9001
- HS Code: 79674545
- Product Name: Lincomycin Hydrochloride
- Molecular Formula: C18h34n2o6s. HCl
- Purity: 99%
- Appearance: White Powder
- Trademark: Newwork union
- Origin: China
Assay: More than 800ug/mg.
Content: 84.0 per cent to 93.0 per cent of clindamycin (C18H33ClN2O5S) (anhydrous substance).
Packing: 25KG/cardboard drum
Appearance: White or almost white, crystalline powder.
Solubility: Very soluble in water, slightly soluble in alcohol.
Clindamycin HCl is an antibiotic recommended for the therapy of a few bacteria-related illnesses.
Antibiotics treat bacterial infections by preventing bacteria from growing. Clindamycin HCl works most effectively to stop infections caused by anaerobic bacteria--bacteria that do not need oxygen to survive--such as Staphylococcus aureus and Streptopcoccus pneumonia. Clindamycin inhibits the manufacture of protein by the bacteria, disabling their ability to replicate. Any bacteria remaining quickly die out, and no new bacteria are able to survive in the presence of clindamycin, which effectively stops the infection being treated.
Assay: More than 75.8%.
Standard: USP32, BP, EP
Packing: 25KG/cardboard drum
CHARACTERS: A white or almost white powder, slightly hygroscopic, freely soluble in water, very slightly soluble in alcohol, practically insoluble in methylene chloride.
Function: Antibiotic raw material, in vitro activity, rapidly hydrolyzed to clindamycin for the antibacterial function after entering into the body.
Storage: Sealed and preserved in tight container.
Formula: C18H34N2O6S. HCl
Molecular Weight: 443.06
Melting Point: 156-158 ° C
Boiling Point: 646.8 ° C at 760 mmHg
Flash Point: 345 ° C
Package: 20kg/drum or as your requirements
Usage: Application: Is a type of antibiotics, used to treat infections caused by gram-negative bacteria, gram-positive bacteria and mycoplasma.
|Characters||White or practically white,crystalline powder||White crystalline powder|
|Solubility||Freely soluble in water, in dimethylformamide, and in methanol;soluble in alcohol;practically insoluble in acetone||Conform|
|Related compounds||≤2.0% clindamycin B||0.87%|
|≤1.0% any other individual related compound||0.19%|
|≤6.0% total of all related compound||2.20%|
|Residual solvents||Acetone ≤5000ppm||91ppm|
|Ethanol ≤5000ppm||No detected|
|Assay||Not less than 800μg of clindamycin (C18H33ClN2O5S)per mg||862 μg/mg|
Lincomycin is a lincosamide antibiotic that comes from the actinomyces Streptomyces lincolnensis. A related compound, clindamycin, is derived from lincomycin by using thionyl chloride to replace the 7-hydroxy group with a chlorine atom with inversion of chirality.
Although similar in structure, antibacterial spectrum, and mechanism of action to macrolides, lincomycin is also effective against other organisms including actinomycetes, mycoplasma, and some species of Plasmodium. Intramuscular administration of a single dose of 600 mg of Lincomycin produces average peak serum levels of 11.6 micrograms/ml at 60 minutes, and maintains therapeutic levels for 17 to 20 hours, for most susceptible gram-positive organisms. Urinary excretion after this dose ranges from 1.8 to 24.8 percent (mean: 17.3 percent).
A two-hour intravenous infusion of 600 mg of Lincomycin achieves average peak serum levels of 15.9 micrograms/ml and yields therapeutic levels for 14 hours for most susceptible gram-positive organisms. Urinary excretion ranges from 4.9 to 30.3 percent (mean: 13.8 percent).
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